Fatal Plasmodium falciparum Malaria after an Inadequate Response to Quinine Treatment
Identifieur interne : 003032 ( Main/Exploration ); précédent : 003031; suivant : 003033Fatal Plasmodium falciparum Malaria after an Inadequate Response to Quinine Treatment
Auteurs : Sornchai Looareesuwan [Canada, Thaïlande] ; Poonkasem Charoenpan [Canada] ; May Ho [Canada] ; Nicholas J. White [Canada] ; Juntra Karbwang [Canada] ; Danai Bunnag [Canada] ; Tranakchit Harinasuta [Canada]Source :
- Journal of Infectious Diseases [ 0022-1899 ] ; 1990.
Abstract
A 24-year-old man with severe Plasmodium falciparum malaria died after 77 h of treatment with full parenteral doses of quinine. His peripheral parasitemia at death exceeded the level on admission. Plasma concentrations of quinine were abnormally low throughout. This case emphasizes the importance of pharmacokinetic factors in determining the therapeutic response in severe P. falciparum malaria.
Url:
DOI: 10.1093/infdis/161.3.577
Affiliations:
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His peripheral parasitemia at death exceeded the level on admission. Plasma concentrations of quinine were abnormally low throughout. This case emphasizes the importance of pharmacokinetic factors in determining the therapeutic response in severe P. falciparum malaria.</div></front></TEI><affiliations><list><country><li>Canada</li><li>Thaïlande</li></country></list><tree><country name="Canada"><noRegion><name sortKey="Looareesuwan, Sornchai" sort="Looareesuwan, Sornchai" uniqKey="Looareesuwan S" first="Sornchai" last="Looareesuwan">Sornchai Looareesuwan</name></noRegion><name sortKey="Bunnag, Danai" sort="Bunnag, Danai" uniqKey="Bunnag D" first="Danai" last="Bunnag">Danai Bunnag</name><name sortKey="Charoenpan, Poonkasem" sort="Charoenpan, Poonkasem" uniqKey="Charoenpan P" first="Poonkasem" last="Charoenpan">Poonkasem Charoenpan</name><name sortKey="Harinasuta, Tranakchit" sort="Harinasuta, Tranakchit" uniqKey="Harinasuta T" first="Tranakchit" last="Harinasuta">Tranakchit Harinasuta</name><name sortKey="Ho, May" sort="Ho, May" uniqKey="Ho M" first="May" last="Ho">May Ho</name><name sortKey="Karbwang, Juntra" sort="Karbwang, Juntra" uniqKey="Karbwang J" first="Juntra" last="Karbwang">Juntra Karbwang</name><name sortKey="White, Nicholas J" sort="White, Nicholas J" uniqKey="White N" first="Nicholas J." last="White">Nicholas J. White</name></country><country name="Thaïlande"><noRegion><name sortKey="Looareesuwan, Sornchai" sort="Looareesuwan, Sornchai" uniqKey="Looareesuwan S" first="Sornchai" last="Looareesuwan">Sornchai Looareesuwan</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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